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Levitra dosage. 6 months or longer, and 880 patients were treated for at least 1 year. In placebo-controlled clinical trials, the discontinuation rate due to adverse events was 3.4% for LEVITRA compared to 1.1% for placebo. When LEVITRA was taken as recommended in placebo-controlled clinical trials, the following adverse events were reported (see Table 5). Table 5: Adverse Events Reported By & 179;2% of Patients Treated with LEVITRA and More Frequent on Drug than Placebo in Fixed and Flexibleg Dose Randomized, Controlled Trials of 5 mg, 10 mg, or 20 mg Vardenafil Adverse Event Percentage of Patients Reporting Event Placebo N = 1199 LEVITRA N = 2203 Headache 4% 15% Flushing 1% 11% Rhinitis 3% 9% Dyspepsia 1% 4% Accidental Injury* 2% 3% Sinusitis 1% 3% Flu Syndrome 2% 3% Dizziness 1% 2% Increased Creatine Kinase 1% 2% Nausea 1% 2% * All the events listed in the above table were deemed to be adverse drug reactions with the exception of accidental injury. gFlexible dose studies started all patients at LEV levitra dosage

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ITRA 10 mg and allowed decrease in dose to 5 mg or increase in dose to 20 mg based on side effects and efficacy. Back pain was reported in 2.0% of patients treated with LEVITRA and 1.7% of patients on placebo. Placebo-controlled trials suggested a dose effect in the incidence of some adverse events (headache, flushing, dyspepsia, nausea, rhinitis) over the 5 mg, 10 mg, and 20 mg doses of LEVITRA. The following section identifies additional, less frequent events (<2%) reported during the clinical development of LEVITRA. Excluded from this list are those events that are infrequent and minor, those events that may be commonly observed in the absence of drug therapy, and those events that are not reasonably associated with the drug. BODY AS A WHOLE: anaphylactic reaction (including laryngeal edema), asthenia, face edema, pain AUDITORY: tinnitus CARDIOVASCULAR: angina pectoris, chest pain, hypertension, hypotension, myocardial ischemia, myocardial infarction, palpitation, postural hypote levitra dosage

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levitra dosage N CYP1A2 levitra dosage, 2A6 levitra dosage, and 2E1 (Ki >100 mM). Weak inhibitory effects toward other isoforms (CYP2C8 levitra dosage, 2C9 levitra dosage, 2C19 levitra dosage, 2D6 levitra dosage, 3A4) were found levitra dosage, but Ki values were in excess of plasma concentrations achieved following dosing. The most potent inhibitory activity was observed for vardenafil metabolite M1 levitra dosage, which had a Ki of 1.4 mM toward CYP3A4 levitra dosage, which is about 20 times higher than the M1 Cmax values after an 80 mg LEVITRA dose. In vivo studies: Nitrates: The blood pressure lowering effects of sublingual nitrates (0.4 mg) taken 1 and 4 hours after vardenafil and increases in heart rate when taken at 1 levitra dosage, 4 and 8 hours were potentiated by a 20 mg dose of LEVITRA in healthy middle-a levitra dosage.

levitra dosage Ged subjects. These effects were not observed when LEVITRA 20 mg was taken 24 hours before the NTG. Potentiation of the hypotensive effects of nitrates for patients with ischemic heart disease has not been evaluated levitra dosage, and concomitant use of LEVITRA and nitrates is contraindicated (see CLINICAL PHARMACOLOGY levitra dosage, Pharmacodynamics levitra dosage, Effects on Blood Pressure and Heart Rate when LEVITRA is Combined with Nitrates; CONTRAINDICATIONS). Nifedipine: Vardenafil 20 mg levitra dosage, when co-administered with slow-release nifedipine 30 mg or 60 mg once daily levitra dosage, did not affect the relative bioavailability (AUC) or maximum concentration (Cmax) of nifedipine levitra dosage, a drug that is metabolized via CYP3A4. Nifedipine did not alter the plasma levels of LEVITRA when taken in combination. In these patients whose hypertension was controlled with nifedipine levitra dosage, LEVITRA 20 mg produced mean additional supine systolic diastolic blood pressure reductions of 6 5 mmHg compared to placebo. Alpha-blockers: Blood pressure effects in patients on stable alpha-blocker treatment: Two clinical pharmacology studies were conducted in patients with benign prostatic hyperplasia (BPH) on stable-dose alpha-blocker treatment for at least four weeks. Study 1: This study was designed to evaluate the effect of 5 mg vardenafil compared to placebo when administered to BPH patients on chroni.

levitra dosage 4. Nifedipine did not alter the plasma levels of LEVITRA when taken in combination. In these patients whose hypertension was controlled with nifedipine levitra dosage, LEVITRA 20 mg produced mean additional supine systolic diastolic blood pressure reductions of 6 5 mmHg compared to placebo. Alpha-blockers: Blood pressure effects in patients on stable alpha-blocker treatment: Two clinical pharmacology studies were conducted in patients with benign prostatic hyperplasia (BPH) on stable-dose alpha-blocker treatment for at least four weeks. Study 1: This study was designed to evaluate the effect of 5 mg vardenafil compared to placebo when administered to BPH patients on chronic.

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